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BAST JR, ROBERT C
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BAST JR, ROBERT C
Item Type
Name
Academic Article
Heregulin-induced apoptosis is mediated by down-regulation of Bcl-2 and activation of caspase-7 and is potentiated by impairment of protein kinase C alpha activity.
Academic Article
Transcriptional and posttranscriptional down-regulation of the imprinted tumor suppressor gene ARHI (DRAS3) in ovarian cancer.
Academic Article
The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis.
Academic Article
Use of Ras-transformed human ovarian surface epithelial cells as a model for studying ovarian cancer.
Concept
Tumor Cells, Cultured
Concept
Cells, Cultured
Academic Article
A combination of two immunotoxins exerts synergistic cytotoxic activity against human breast-cancer cell lines.
Academic Article
Fibronectin is an immunosuppressive substance associated with epithelial ovarian cancer.
Academic Article
Immunopharmacologic purging of breast cancer from bone marrow for autologous bone marrow transplantation.
Academic Article
Coordinate expression of urinary-type plasminogen activator and its receptor accompanies malignant transformation of the ovarian surface epithelium.
Academic Article
Heregulin and agonistic anti-p185(c-erbB2) antibodies inhibit proliferation but increase invasiveness of breast cancer cells that overexpress p185(c-erbB2): increased invasiveness may contribute to poor prognosis.
Academic Article
Detection of minimal residual breast cancer in bone marrow.
Academic Article
Expression and amplification of the HER-2/neu (c-erbB-2) protooncogene in epithelial ovarian tumors and cell lines.
Academic Article
Epidermal growth factor receptor expression in normal ovarian epithelium and ovarian cancer. II. Relationship between receptor expression and response to epidermal growth factor.
Academic Article
Use of immunotoxins in combination to inhibit clonogenic growth of human breast carcinoma cells.
Academic Article
Differential induction by interferons of major histocompatibility complex-encoded and non-major histocompatibility complex-encoded antigens in human breast and ovarian carcinoma cell lines.
Academic Article
Constitutive production of macrophage colony-stimulating factor by human ovarian and breast cancer cell lines.
Academic Article
Effects of monoclonal antibody and complement treatment of human marrow on hematopoiesis in continuous bone marrow culture.
Academic Article
Acquired cellular immunity: extracellular killing of Listeria monocytogenes by a product of immunologically activated macrophages.
Academic Article
Aryl hydrocarbon (benzo(alpha)pyrene) hydroxylase in guinea pig peritoneal macrophages: benz(alpha)anthracene-induced increase of enzyme activity in vivo and in cell culture.
Academic Article
Antibody-induced growth inhibition is mediated through immunochemically and functionally distinct epitopes on the extracellular domain of the c-erbB-2 (HER-2/neu) gene product p185.
Academic Article
Regulation of tumour necrosis factor-alpha processing by a metalloproteinase inhibitor.
Academic Article
Transfection of ovarian cancer cells with tumor necrosis factor-alpha (TNF-alpha) antisense mRNA abolishes the proliferative response to interleukin-1 (IL-1) but not TNF-alpha.
Academic Article
Alkylating agents and immunotoxins exert synergistic cytotoxic activity against ovarian cancer cells. Mechanism of action.
Academic Article
Tumor necrosis factor alpha as an autocrine and paracrine growth factor for ovarian cancer: monokine induction of tumor cell proliferation and tumor necrosis factor alpha expression.
Academic Article
The effect of antibodies and immunotoxins reactive with HER-2/neu on growth of ovarian and breast cancer cell lines.
Academic Article
Radioiodinated antibody targeting of the HER-2/neu oncoprotein.
Academic Article
Expression of p16 induces transcriptional downregulation of the RB gene.
Academic Article
Suppression of diacylglycerol levels by antibodies reactive with the c-erbB-2 (HER-2/neu) gene product p185c-erbB-2 in breast and ovarian cancer cell lines.
Academic Article
Breast cancer cells are effectively purged from peripheral blood progenitor cells with an immunomagnetic technique.
Academic Article
Expression of p53 in cisplatin-resistant ovarian cancer cell lines: modulation with the novel platinum analogue (1R, 2R-diaminocyclohexane)(trans-diacetato)(dichloro)-platinum(IV).
Academic Article
Decreased Src tyrosine kinase activity inhibits malignant human ovarian cancer tumor growth in a nude mouse model.
Academic Article
The outcome of heregulin-induced activation of ovarian cancer cells depends on the relative levels of HER-2 and HER-3 expression.
Academic Article
Inhibition of growth-factor-induced phosphorylation and activation of protein kinase B/Akt by atypical protein kinase C in breast cancer cells.
Academic Article
Regulation of invasion of epithelial ovarian cancer by transforming growth factor-beta.
Academic Article
Genomic structure and promoter characterization of an imprinted tumor suppressor gene ARHI.
Academic Article
Genetic analysis of early- versus late-stage ovarian tumors.
Academic Article
Fluorescence spectroscopy as a biomarker in a cell culture and in a nonhuman primate model for ovarian cancer chemopreventive agents.
Academic Article
Activated SRC protein tyrosine kinase is overexpressed in late-stage human ovarian cancers.
Academic Article
The role of cyclin-dependent kinase inhibitor p27Kip1 in anti-HER2 antibody-induced G1 cell cycle arrest and tumor growth inhibition.
Academic Article
Epigenetic regulation of ARHI in breast and ovarian cancer cells.
Academic Article
Overexpression of kallikrein 10 in epithelial ovarian carcinomas.
Academic Article
Aberrant methylation and silencing of ARHI, an imprinted tumor suppressor gene in which the function is lost in breast cancers.
Academic Article
Overexpression of MEKK3 confers resistance to apoptosis through activation of NFkappaB.
Academic Article
Induction of tumor immunity by intratumoral chemotherapy.
Academic Article
Development of an assay for aryl hydrocarbon (benzo(a)pyrene) hydroxylase in human peripheral blood monocytes.
Academic Article
The effect of interferon gamma on epidermal growth factor receptor expression in normal and malignant ovarian epithelial cells.
Academic Article
Synergistic cytotoxicity of different alkylating agents for epithelial ovarian cancer.
Academic Article
Heterogeneity of antigen expression in advanced epithelial ovarian cancer.
Academic Article
Long-term culture of human granulocytes and granulocyte progenitor cells.
Academic Article
Treatment of murine peritoneal macrophages with bacterial lipopolysaccharide alters expression of c-fos and c-myc oncogenes.
Academic Article
Presence of A-type and absence of C-type virus particles in a chemically induced guinea pig hepatoma.
Academic Article
Monocyte chemotaxis mediated by formyl-methionyl-leucyl-phenylalanine conjugated with monoclonal antibodies against human ovarian carcinoma.
Academic Article
Transforming growth factor beta 1 can induce CIP1/WAF1 expression independent of the p53 pathway in ovarian cancer cells.
Academic Article
Transforming growth factor-beta inhibits proliferation of human ovarian cancer cells obtained from ascites.
Academic Article
Secretion of extracellular matrix-degrading proteinases is increased in epithelial ovarian carcinoma.
Academic Article
Overexpression of the tyrosine phosphatase PTP1B is associated with human ovarian carcinomas.
Academic Article
Constitutive production of macrophage colony-stimulating factor and interleukin-6 by human ovarian surface epithelial cells.
Academic Article
Cell surface density of p185(c-erbB-2) determines susceptibility to anti-p185(c-erbB-2)-ricin A chain (RTA) immunotoxin therapy alone and in combination with anti-p170(EGFR)-RTA in ovarian cancer cells.
Academic Article
Relative cytotoxic activity of immunotoxins reactive with different epitopes on the extracellular domain of the c-erbB-2 (HER-2/neu) gene product p185.
Academic Article
Adenovirus-mediated p53 growth inhibition of ovarian cancer cells is independent of endogenous p53 status.
Academic Article
Lysophosphatidic acid induces urokinase secretion by ovarian cancer cells.
Academic Article
Overexpression of edg-2/vzg-1 induces apoptosis and anoikis in ovarian cancer cells in a lysophosphatidic acid-independent manner.
Academic Article
Future for ovarian cancer screening: novel markers from emerging technologies of transcriptional profiling and proteomics.
Academic Article
Reexpression of the tumor suppressor gene ARHI induces apoptosis in ovarian and breast cancer cells through a caspase-independent calpain-dependent pathway.
Academic Article
Paclitaxel induces inactivation of p70 S6 kinase and phosphorylation of Thr421 and Ser424 via multiple signaling pathways in mitosis.
Academic Article
Establishment and characterization of cancer cell cultures and xenografts derived from primary or metastatic Mullerian cancers.
Academic Article
Proteomics analysis of H-RAS-mediated oncogenic transformation in a genetically defined human ovarian cancer model.
Academic Article
Imprinted tumor suppressor genes ARHI and PEG3 are the most frequently down-regulated in human ovarian cancers by loss of heterozygosity and promoter methylation.
Academic Article
A phosphopeptide mimetic prodrug targeting the SH2 domain of Stat3 inhibits tumor growth and angiogenesis.
Academic Article
Regulation of growth of normal ovarian epithelial cells and ovarian cancer cell lines by transforming growth factor-beta.
Academic Article
[Synergistic antitumor activity of human breast cancer immunotoxins].
Academic Article
The role of peptide growth factors in epithelial ovarian cancer.
Academic Article
Homologous and heterologous desensitization of proto-oncogene cfos expression in murine peritoneal macrophages.
Academic Article
Absence of common ALL antigen on normal bipotent myeloid, erythroid, and granulocyte progenitors.
Academic Article
Regulation of apoptosis in normal and malignant ovarian epithelial cells by transforming growth factor beta.
Academic Article
Specificity and affinity of 26 monoclonal antibodies against the CA 125 antigen: first report from the ISOBM TD-1 workshop. International Society for Oncodevelopmental Biology and Medicine.
Academic Article
Anti-HER2 antibody and heregulin suppress growth of HER2-overexpressing human breast cancer cells through different mechanisms.
Academic Article
Differential signaling by an anti-p185(HER2) antibody and heregulin.
Academic Article
Functional evidence for an ovarian cancer tumor suppressor gene on chromosome 22 by microcell-mediated chromosome transfer.
Academic Article
Anti-HER2 antibody trastuzumab inhibits CDK2-mediated NPAT and histone H4 expression via the PI3K pathway.
Academic Article
Stimulation of ovarian tumor cell proliferation with monocyte products including interleukin-1, interleukin-6, and tumor necrosis factor-alpha.
Academic Article
Detection of breast carcinoma cells in human bone marrow using fluorescence-activated cell sorting and conventional cytology.
Academic Article
The tyrosine kinase activity of the C-erbB-2 gene product (p185) is required for growth inhibition by anti-p185 antibodies but not for the cytotoxicity of an anti-p185-ricin-A chain immunotoxin.
Academic Article
Expression of alpha 6 and beta 4 integrins in serous ovarian carcinoma correlates with expression of the basement membrane protein laminin.
Academic Article
Activation of the ras-mitogen-activated protein kinase pathway and phosphorylation of ets-2 at position threonine 72 in human ovarian cancer cell lines.
Academic Article
Radioiodinated antibody targeting of the HER-2/neu oncoprotein: effects of labeling method on cellular processing and tissue distribution.
Academic Article
Synergistic interaction between anti-p185HER-2 ricin A chain immunotoxins and radionuclide conjugates for inhibiting growth of ovarian and breast cancer cells that overexpress HER-2.
Academic Article
Synergistic interaction between an anti-p185HER-2 pseudomonas exotoxin fusion protein [scFv(FRP5)-ETA] and ionizing radiation for inhibiting growth of ovarian cancer cells that overexpress HER-2.
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Cells Cultured